Conveniently located in the heart of Irvine's one of main business districts, Irvine Airport Area is within easy reach of John Wayne Airport (SNA) as well as with easy access to the 405 and 55 Freeways and 73 Toll Road. John Wayne The area is surrounded by a wide variety of shops, restaurants, hotels, offices, banks, upscale neighborhoods and other services and amenities. The upscale shopping centers South Coast Plaza and Fashion Island are very close to the area.